Experiments: HCV can live in water bottles for up to three weeks

This study title caught my eye: Transmission of Hepatitis C Virus Among People Who Inject Drugs: Viral Stability and Association With Drug Preparation Equipment (LINK). • JID 2013:207 (15 January) • Doerrbecker et al

PDF:  Full Text. hcv in water

“We found that, depending on the viral dose, HCV can survive in water for >3 weeks and might thereby contribute to ongoing transmission of HCV in PWID networks when water is reused or shared. These results are in line with data showing the stability of the virus in serum for 3–4 weeks”  (LINK to footnoted study/doi: 10.1086/652803)

red bull

“The can had probably the highest association with HCV among the evaluated water containers because more of the original HCV-inoculated water remained in the can before it was refilled, owing to the can’s small opening.” Image: viZZZual on Flickr

IDUers help HCV move on to new victims when they prepare their drug works. It clings to plastic, aluminium cans (Red Bull), but not so much, glass (Coca-Cola). It gets on everything; no blood (serum) is needed for it to remain stable and infectious.

It is technical so here is a part of the introductory summary (edited):

Background.

We investigated the risk of HCV transmission by analyzing the direct association of HCV with filters, water to dilute drugs, and water containers.

Methods.

Experiments were designed to replicate practices by people who inject drugs and include routinely used injection equipment. HCV stability in water was assessed by inoculation of bottled water with HCV. Viral association with containers was investigated by filling the containers with water, inoculating the water with HCV, emptying the water, and refilling the container with fresh water. Transmission risk associated with drug preparation filters was determined after drawing virus through a filter and incubating the filter to release infectious particles.

HCV can survive for up to 3 weeks in bottled water. Water containers present a risk for HCV transmission, as infectious virions remained associated with water containers after washing. Physical properties of the water containers determined the degree of HCV contamination after containers were refilled with water. HCV was also associated with filter material, in which around 10% of the viral inoculum was detectable.

In short, it takes a lot of effort to render HCV that “exists” outside of a human body harmless.  It survives high heat, all manner of chemicals, freeze-drying, being left on a wide variety of surfaces and neglected for weeks in the open air.  HCV doesn’t need blood to “live” in hostile environments but it eventually will fizzle out if it can’t hitch a ride into a new human body. In water, blood, powder, it’s all good as far as HCV is concerned.

Not picky outside of human bodies

HCV is not picky about its habitat outside of human bodies while waiting to slip into a new one. And it is patient and can handle extreme environments.

So is it really accurate to think of HCV as a limited blood-borne pathogen when even liquids like drinking water can be an intermediary step between carrier A to carrier B?  It makes the VA’s approved “HCV risk factor” lists,  C & P exams (most) and BVA HCV denial decisions even more ludicrous in the light of all the new information that is being published.  Referencing this study may be useful in the HCV claims process.  

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“Six degrees of separation” by Daniel’ (User:Dannie-walker) – Own work. Licensed under CC BY-SA 3.0 via Commons –

The degree of separation (think Kevin Bacon Six Degrees of Separation (BBC video) between any veterans harboring HCV while in-service and those who were not, was very slim. Consider contaminated possessions and it’s slimmer still.  (I suppose learning a bit about network theories should be on our agendas.)

Posted in BvA HCV decisions, Complaints Department, Food for thought, Guest authors, Medical News, research, Uncategorized, Vietnam Disease Issues | Leave a comment

FACEPLACE CHRISTMAS–KEEPERS

521984_10151158220335700_1167099371_nSearching through the mails with an eye for obnoxious is a task for the devoted. Finding just the right off-key emotion, the sarcastic rejoinder or dissatisfaction with the status quo of life is the essence of humor. Of course, being born on April Fool’s day gives you a leg up. For me, everything is humorous-or should be. 

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CBS news report (12/1/15): most veterans denied HCV meds

We have all read news stories about the difficulty veterans with active chronic HCV infection are having getting treated with Sovaldi at the VA. Some articles express a more reality-based report on the service-connected HCV outbreak among Vietnam veterans.   Is there a shift in attitude away from the offensive myth of widespread IVDU in this much maligned veteran population?  

Although we know that IVDU was rare in Vietnam from a 1973 government report, service persons who did engage in this behavior were a health menace to their comrades in combat and during any other events when their blood was transferred on and into another person’s body and blood stream..  (They were a menace to sex workers too.) During a typical tour of duty in Vietnam, exposure to IVDUers bodies, dead or alive, were in fact a service-connected HCV risk factor that should be added to the existing long long list of SC risk factors.  

But the most devastating transmissions of hepatitis occurred during transfusions due to the huge viral loads in the blood bags.  CBS (LINK):  

cbs

“In 2013, Vietnam veteran Zion Yisrael (right, CBS image) was told he had five years to live. He has stage 4 liver disease, caused by hepatitis C — which has infected as many as 230,000 veterans. Most veterans contracted it in Vietnam where it was spread by battlefield blood transfusions and vaccinations.

So far they have treated about 35,000 veterans, that’s just 15 percent of the veterans infected with hepatitis C.”

Gilead’s gouging policy has resulted in even fewer Medicaid HCV patients getting treated–only 3%.  According to the Senate Finance Committee press conference, “…in 2014, Medicaid programs spent $1 billion on Gilead’s Hepatitis C drugs, yet more than 97% of Medicaid patients went untreated.”  Medicare costs were even higher.

The  144-page bipartisan report is a marketing case study. The pdf link is below.

 SFC Sovaldi Report Executive Summary1 The Price of Sovaldi and Its Impact on the U.S. Health Care System (Full Report) 

Recent VA research (Nov. 14, 2015) gives different numbers using 2013 VA databases.

Cascade of Care for Hepatitis C Virus Infection Within the US Veterans Health Administration (Link to abstract on PUBMED).

OBJECTIVES:  We measured the quality of HCV care using a cascade of HCV care model.

METHODS:

We estimated the number of patients diagnosed with chronic HCV, linked to HCV care, treated with HCV antivirals, and having achieved a sustained virologic response (SVR) in the electronic medical record data from the Veterans Health Administration’s Corporate Data Warehouse and the HCV Clinical Case Registry in 2013.

RESULTS:

 Of the estimated 233,898 patients with chronic HCV, 77% (181,168) were diagnosed, 69% (160 794) were linked to HCV care, 17% (39,388) were treated with HCV antivirals, and 7% (15,983) had achieved SVR.

From the SFC’s report, “Prior to the virus’ identification in 1989, HCV was frequently spread through unscreened blood transfusions.”  

Definitions and synonyms for the word “frequently”:  all the time, habitually, very often, commonly, usually, as a rule, , ordinarily, again and again, over and over, repeatedly, regularly, routinely, more often than not and other none precise terms which sometimes can be quantified.   Pick your favorites.  I like “more often than not” and “all the time.”  

The military had been working on the hepatitis-transfusion problem decades before the “Vietnam Misunderstanding” as Nod sometimes puts it.  But the technologies had to be developed before anything could be done to break the chain of transmissions as each hepatitis virus was identified. transfuion korea

 Korean War transfusions.  Image: Walter Reed.

Posted in Blood info, Congressional HCV info, Congressional Influence, Guest authors, HCV Risks (documented), transfusions and hepatitis, VA Health Care, Vietnam Disease Issues | Tagged , , , , , , , , , , , , , , , , , , , , , , | 14 Comments

BLOG TAWK RADIDIO WITH JERREL COOK

haditlogo2007Jerrel has graciously invited me over for another hour of radio chat on his favorite subject (and mine). If VA ever quit stepping on their necktie, we’d be out of subjects to discuss. Unfortunately, that’s about as likely as pigs with a FAA ticket. While I have little endemic knowledge of Social Security issues, I do have a wealth of observing what happens around the VA if you don’t have those SSI records on board in many of the claims we file.

Microphones are cleared in hot in one Hour   (1600 HRS L Seattle)

Park your ear over at Hadit’s Blog Talk Radio number and refuel your brain tomorrow again. Given an hour, there’s no telling what kind of trouble we can get into.

The call in number remains…

347-237-4819

I’m sure they haven’t fired the gal who greets us. Dial one (the digit) when you get there. Never feel you’re interrupting us when we’re flapping our lips. We welcome your questions-even if we can’t answer them.

If posssible, I’d like to discuss the SSI type of thing that occurs more frequently than you can imagine.

http://www.justice.gov/usao-sdfl/pr/department-veterans-affairs-nurse-convicted-falsifying-medical-records-and-computer.

We in the business like to call it a “Cushman violation” named after one of our own, Phil Cushman, who caught them at it…while he was alive. I, too, have one of these stories to tell of one in West LA.

And for your Tuesday morning humor, Law Bob Squarepant’s choice cuts out of Africa

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FACEPLACE– 2015 WINNERS

1455973_692271310791851_2118973843_nThe usual roundup of 2015’s choice cuts. Politically culled to offend no one. Recognizing the excellence of your submissions this year, I will give credit to those who did. Wait. Scratch that. 

 

 

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HADIT.COM RADIO SHOW ON THURSDAY PM

haditlogo2007Jerrel Cook called me while I was swamping out the stalls this evening and preparing to feed the monsters. This threw everything into a tailspin. Cooper and Kona have food rules and they don’t cotton to me yakking it up on the phone during their perceived Horsey Happy Hour. Beet pulp is served stirred, not shaken- and always on time. For the next 10 minutes I was double teamed with horse lips by the two until I relented and said goodbye. I ended up with three hickies.

Jerrel says we can talk about whatever we want to. Showtime is 1900 hrs Congressional Wasting Disease time (for you on the east coast) and 1600 Hrs on the Left Coast. Please feel free to call in with any questions. We’ll talk about a wide range of subjects and my new book.

The call in number is still the same.

347-237-4819

The gal with the cute British accent will be answering and giving you prompts on getting on to the show. Christmas presents are optional again this year but we do accept donations in small, unmarked bills that are difficult to trace. We’ll give you the  P.O. drop box address tomorrow evening.

ss-call-me

Welcome to Blawg Tawk rädio, ‘andsome.

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ILP-HANG IN THERE. WE NEED GUIDANCE ON THIS. NOBODY EVER WON.

Jack-KammererAfter waiting patiently now for over three months  for my Seattle VR&E minder, Kris Holloway, to push print on my greenhouse, I decided to call him up and rattle the ILP cage. True to form, he let it go onto Voicemail after being informed it was the asknod puke from Gig Harbor. I expected no less. His answer arrived this morning.

HOLLAWAY, KRIS, VBASEAT <kris.hollaway@va.gov>

To

asknod@gmail.com
Today at 11:16 AM
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BVA–METAVIR SCORE– STAGE 1≠ 1972

 FROM THE FT. SUMTER MEMORIAL REGIONAL TOWER OF BABEL

Here’s an interesting decision that illustrates the aging of Hepatitis C. Just like a good single malt from Scotland is carefully aged, Hepatitis C bakes your liver at a slow rolling boil just below the level of perception and annoyance. Come to think of it, both of them do! Fatigue and vague digestive issues are your only overt indicator until the trapdoor opens and the bottom fall out of your life.

I’ve long taught and advised doctors and attorneys about this simple way of dating the disease. Gastroenterologists, and their hepatic digestive specialists called hepatologists, long ago devised a simple carbon dating system for liver boxes. Since there are several distinctly different methods of expressing it in numbers, I like to use the Metavir Scale for several reasons. The foremost is it is also used by the VA. There is no need to cross-rate it from the Child-Pughs Scale and it is far simpler to express in numbers. It is gaining much wider acceptance as the universal measurement much like meters over miles.

As an example of one of the reasons I won, my doctor cited to my rather advanced disease based on a core biopsy performed in January of 2007. Expressed in Metavirese, I was Stage 3 (F3) and Grade 3 (A3) and headed to Hell lickitysplit without some immediate medical intervention pronto.

Each stage of fibrosis is approximately ten years. It can stretch to 13-14 if you don’t drink or smoke (tobacco). The jury is still out on how hootch affects it. If you drink a lot of coffee, that will cleanse the liver. If you were/are a naturopathic imbiber of Milk thistle, you could also retard the inevitable. Eventually, nothing will hold back the tide and your liver will succumb to cirrhosis and a transplant will be in order. Or, you get hepatocellular carcinoma (HCC) and they tell you to get lost and die.

downloadAfter you get a liver biopsy, you can begin to mark time geologically based on the results. You can march back in time 10-12 years for each of those stages of fibrosis to get a chronological dead reckoning of the beginning of the problem. You may or may not recognize any significant medical  event that began this either. That is immaterial. The biopsy cannot lie as to the age of the infection. Which brings us to Johnny Rebel here from the Columbia, South Carolina Puzzle Palace. Here’s Johnny’s tale of woe and an interesting observation by a VA examiner.

From the get go, the Johnster has an intriguing story of his Welcome To Germany greeting by his barracks mates. I disremember a lot but I sure don’t think I ever was greeted like him when I got to Udorn. I remember the Singha ETOH greeting with a Jack Daniels back. And considering I never left home without a Model 19 and my American Express card, throwing a blanket over me might have been a very short-lived blanket party.

[t]he Veteran provided a statement dated in April 2012 regarding an assault in service which he contends caused his hepatitis. Specifically, the Veteran reports he was sent to a duty station in Mainz, Germany. When he arrived, he went to take a short nap following the long flight. At that time, soldiers in his room attacked him, pulled the covers over him and held his arms and legs down. He was surrounded with smoke and a needle was stuck in his arm with chemicals.

The VA examiner ( the ARNP poobah) at Fort Columbia allowed as:

“The Veteran had hepatitis in the military which appears to have resolved by 1973. He had no further issues until a diagnosis in 2003. He had stage I fibrosis in 2007. If he had hepatitis consistently since 1972, his liver damage would be much more pronounced than Stage I only”.

This is interesting on two fronts. Obviously, VA teaches how to do these claims from a nationwide perspective and the same medical/M 21 handbook of denial. So why is it that one VA examiner (here) can opine that a Vet was diagnosed in 2003 and include probative medical knowledge supported by proven core biopsy but… Within the last year or three, I have read numerous ” VA examiners” opine just as vociferously that a Vet was “first diagnosed” with it in 2003 and that is the “date of infection”. Nary a mention of Metavir or Child-Pugh grading is to found in their nexus to identify the approximate date of inception.  Either they have a pre-denial mentality with a fill-in-the-blanks program to support it or they are far more knowledegable than they are letting on.

First, without tarring and feathering Johnboy, I will mention two words -Army and Germany. For most who went to Germany for the duration of the Vietnam Boundary Dispute, it was a rather cush job. Lots of Hashish, heroin and German ladies of the evening. Lots of drug use/abuse and lots of Hepatitis B-then known as viral hepatitis.

The viral version, as opposed to the food borne infectious (hepatitis A) variety, was a blood borne disease. If you got it in Germany, you were probably shooting up. Again, probably. If you worked in a medical setting, I would grant that a needle stick was an equal opportunity infection vector. But absent any combat blood exposure like we encountered in Southeast Asia or the jetguns in Basic and AIT, risk factors in Germany were few and far between. Chances of getting it (hepatitis B) from sex were infinitesimal. Even more identifiable would be the local European HCV genotype in 1972. It was almost exclusively 1b in that era. With modern air travel, the genotypes are far more homogenized on all continents now. Nevertheless, the common denominator would be a Stage 3 Metavir. Johnny’s is far newer. Stage 1 indicates about 1995 ish at the earliest.

The Johnmeister from Jermany has also made the mistake of putting on the House, M.D. garb and strung a stethoscope around his neck. He profoundly believes the hepatitis in 1972 is the same identical hepatitis filed for here. The lack of nexus is certainly his downfall but he could have logically made this argument and won but for the Metavir revelation.

Building a claim for VA compensation requires lots more than what Johnbo brought to the table. You need Jacks or better to open and a risk factor that doesn’t include fanciful tales of being assaulted with a hypodermic syringe by unknown assailants. I don’t know that he could have made better headway with a VSO or an attorney but he sure didn’t think it through based on medical theory.

Posted in BvA HCV decisions, HCV Health, HCV Risks (documented), Jetgun BvA Decisions, Jetgun Claims evidence, Medical News, Nexus Information | Tagged , , , , , , , , , , , , , , , , , , , | Leave a comment

BAD NEWS FOR CUPCAKE

HCV imageAnd the envelope please? I just received my results of the one-year HCV viral load and ultrasound for HCC. The bad news is Cupcake is stuck with me for eternity unless Agent Orange rears its ugly head. Attached below are the results of the ultrasound and the PCR RNA  viral load tests.  Hooooooooooooooooo, doggies. I might have to buy another horse. 

Again, I have Cupcake to thank. When it became painfully evident that Interferon was my Hemlock in 2007, my twentieth century fox told me to hunker down and preserve what I had left of my health. I was Stage 3 + and grade 3 on the Metavir scale and circling the drain. We went hard core and  inspected everything that went into my body. In spite of it, I still augered in April 23, 2009. From 2010 through my slow recovery, Deb controlled the vertical and horizontal on the diet and the drugs. It was ugly.  If it wasn’t grown on site, I pretty much didn’t eat it. No more Burger Kings and Dilaudid for lunch. The idea was to huddle in place until a new drug came out… like Sovaldi.

Today marks the 363rd day since I completed my 168-day treatment for Hepatitis C. December 7th, 2015 marks the one-year anniversary of the last pill. I had reservations about clearing the virus when many of my contemporaries  who did Interferon relapsed 3-5 years later. I received the ultrasound results confirming no Hepatocellular carcinoma (HCC) last week. The polymerase chain reaction tests are, to me, the confirmation beyond the shadow of a doubt that the dragon is dead.

Negative viral load or HCC

Cupcake fainted. I get that. 28 more years of me is going to be a hard pill to swallow. The good news is that Tourette’s syndrome can be controlled with proper medication-so she has that going for her.

images (1)

 

Posted in HCV Health, Sofosbuvir | Tagged , , , , , , , , , , , , , , , , , , , , | 15 Comments

ASKNOD NEW BOOK

Asknod's  VA Book LogoI’ve received a few calls asking what I’m up to because many of you are not seeing the usual number of posts here. Relax. I’m writing my new book and completing what was unwritten after my last BVA hearing in April 2011. As many know, I lost and had to go to the CAVC on appeal. There, the VA eventually discovered they were wrong. I traveled to DC again this January  for the Mother of all Extraordinary Writs of Mandamus and prevailed once again. 

The new book will be sold as a batch of chapters on the generalities (8) and then focus on individual disabilities with all the tips and tricks I have assembled to win them. Obviously, not all of you need to know about hammertoes or hemorrhoids. Some are going to want to know about the ins and outs of Special Monthly Compensation and filing Extraordinary Writs.

The book will be online only in a .pdf format. It will be sold through Amazon. You can pick and choose among the subjects to find the ones that are pertinent to your circumstances. I will try to keep them as cheap as possible. All proceeds will go to retire the debt on my first printed book which it seems everyone bought in the electronic format for the most part. If it turns into a best seller, we’ll donate anything we make to Fisher House. As most may remember, Cupcake was allowed to stay at the Seattle House for almost two months when it was touch and go in May-June 2009. For that, I owe them an eternal debt. 96% of their donations are plowed right back into the charity because they don’t need the money for exorbitant salaries and funny hats. They don’t have “alumni” other than the wives of Veterans. They don’t send you fancy hats for contributing. In fact, they don’t drown you in requests for more money once you donate.

I did scrounge through all my old photographs to find some period stuff from the war. All print and no color is boring. It surprises me what I managed to keep from over there all these years.

Here’s a sample chapter to get a feel for what’s on the horizon.

New Book Chapter 3- Evidence

This is one of the “basic” chapters rather than an in-depth chapter on a specific subject.

Posted in ASKNOD BOOK, Electronic Filing of Evidence, research, Tips and Tricks | Tagged , , , , , , , , , , , , , , , , , , | 4 Comments