After a five month fight to obtain this magic elixir, I am finally going to proceed on to a six month fight to kill the Dragon. The Decon arrived late today and zero hour’s 9 AM. Protein pills and helmet await me. Words cannot describe the excitement of embarking on this Odyssey. Since the first blast of Interferon almost killed me on April 12th, 2007, I have patiently awaited the onward march of medical science. I theorized that they would come up with a ziploc bag that would encapsulate each virus. Instead, the NS5A inhibitor in Sofosbuvir is a birth control agent. Imagine FedEx throwing $28,000.00 of pills on your back porch. No signature required. It stupefies me. Of course, the whole idea of any medication costing a thousand dollars a pill is almost inconceivable. Almost. A liver transplant is conservatively $550,000.oo. VA planned on making me drive 40 miles to their pharmacy every two weeks for fear I might sell them on the black market.
Much like an application of Frontline Flea juice sterilizes fleas and eliminates them, so too does Sovaldi. It’s probably far more like a birth control pill inasmuch as it interrupts one of the eight or nine critical steps in the viral reproduction.
Treatment of Hepatitis C genotypes 2 and 3 require a twenty four-week course of pills-double the normal 12-week combo therapy for Genotype 1 which still uses the old Interferon poison bug juice. For those of you like Hepsick (Mark) who have already run the gamut of Interferon with no luck, the twenty four-week regimen is also prescribed. Makes sense. If Interferon didn’t kill it the last two times time out, isn’t that the definition of insanity to continue it again and again in hopes of a different, better outcome? Mark thought so. I think it shows Interferon is all washed up. Gilead is introducing the new Sofosbuvir/Ledipasvir double whammy of two different NS5A inhibitors in the new future dose and it won’t involve any ribavirin.
Mark and I both have about the same chance of killing this without the old style crap. My genotype of 3A says 84% with one kicker. If you hit zero bugs in six weeks, you’ll probably win. Mark, with Genotype 1A, had 15 bugs left after four weeks and they didn’t even give him as good odds as they did me. He hit Bingo last Wednesday.
We’ll keep you posted with the Puke Report. News and film at Six every evening. Sovaldi. It’s what’s for dinner. And hey. By rights, Gilead Sciences Stock should have gone up today.